cytotoxic effects of five species of inula against some tumor cell lines

Authors

mahmood mosaddegh

traditional medicine and materia medica research center, shaheed beheshti university of medical sciences, tehran, iran syyed naser ostad

department of toxicology, faculty of pharmacy, tehran university of medical sciences, tehran, iran farzaneh naghibi

traditional medicine and materia medica research center, shaheed beheshti university of medical sciences, tehran, iran maryam h. moghadam

traditional medicine and materia medica research center, shaheed beheshti university of medical sciences, tehran, iran

abstract

the chloroform soluble fractions of ethanolic extracts of five inula belonging to the compositae family were evaluated for cytotoxic activity against five different cell lines including caco2 (human colon adenocarcinoma), mcf7 (human breast adenocarcinoma), hepg2 (human hepatocellular carcinoma), vero (green african monkey kidney) and wehi164 (balb c mouse fibrosarcoma). cytotoxicity was assessed by mtt assay. among these five species, inula oculus christi, exhibited better cytotoxic effects.

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Journal title:
iranian journal of pharmaceutical sciences

جلد ۲، شماره ۴، صفحات ۲۰۳-۲۰۸

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